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About Tamiflu 75 mgIndications: Tamiflu - the antiviral drug which is effective in treating influenza virus h1n1
Recommended by the World Health Organization (WHO) for the treatment and prevention of influenza A/H1N1
Tamiflu significantly reduces the period of clinical manifestations of influenza infection, reduces the severity of the disease and reduces the incidence of complications of influenza, which require the use of antibiotics. It can also be used for prophylaxis of influenza, which led to a 92% significantly reduces the incidence of influenza among persons exposed to patients and by 76% - the frequency of clinically established during the influenza outbreak. The drug can be given to including children under the age of one year.
Tamiflu is indicated for the treatment of influenza caused by viruses types A and B in adults and children over 12 years, with duration of symptoms no more than two sutok.Tipichnye flu symptoms appear suddenly and include fever, cough, headache, marked weakness, muscle pain and sore throat.
Dosage: Assign an adult and children over 12 let.Priem should begin as early as possible, when the first symptoms zabolevaniya.Tamiflyu to ingest 75 mg 2 times a day (morning and evening), during meals, for 5 dney.Mozhno taken with food or without regard to meals. Admission during the meal or with a small amount of milk reduces the possibility of gastric diskomfort.Naryadu with Tamiflu, perhaps symptomatic of the appointment in order to facilitate certain forms of influenza, such as zharoponizhayuschih.Dazhe if you already feel much better, treatment should be brought to a conclusion that is to take all 10 capsules of Tamiflu within 5 days. If you forget to take, take the missed dose as soon as you remember about it, but no later than 2 hours before the next appointment. Then continue to take Tamiflu at the usual time. A double dose of Tamiflu should not be accepted. If you miss several doses in a row, consult vrachom.U patients with creatinine clearance above 30 ml / min to adjust the dose does not nuzhno.U patients with creatinine clearance <30 ml / min is recommended to reduce the dose of Tamiflu to 75 mg once daily for 5 days. In patients with renal insufficiency (creatinine clearance <10 mL / min) application of Tamiflu has not been studied, so when his appointment to be careful. Patients with lesions of the liver: a correction dose of Tamiflu is not trebuetsya.Bolnym old age: Tamiflu dosage adjustment is required.
Contra-indications: safety and efficacy of Tamiflu in children under 12 years of age ustanovleny.Vozmozhno during pregnancy if the expected effect of therapy outweighs the potential risk to the fetus and child health (adequate and strictly controlled studies of the safety of pregnant and lactating women have not performed, unknown if excreted oseltamivir and oseltamivir carboxylate in the breast milk of women).
Side effects: Nausea, vomiting, bronchitis, insomnia and golovokruzhenie.V most cases, these reactions do not require lifting preparata.Vozmozhny as diarrhea, abdominal pain, headache, weakness.
Guidance for children and pregnant women: Currently, data on the use of the drug during pregnancy is insufficient to assess the teratogenic effects or fetotoxicity of oseltamivir phosphate. With this in mind, Tamiflu should be prescribed during pregnancy or during lactation only if the anticipated benefits from its use outweighs the potential risk to the fetus or infant. In experimental studies of reproduction in rats and rabbits, teratogenic effects were observed. Instructions for any influence of any of the studied doses of oseltamivir on reproduction has been received. AUC of the drug in the embryos of rats and rabbits was approximately 15-20% of that of the pregnant females. In lactating rats, oseltamivir and active metabolite are allocated to milk. Provided whether oseltamivir or its active metabolite with milk in humans is unknown.
Cautions: The effectiveness of the treatment of patients with chronic heart and / or respiratory ustanovlena.Ne not observed differences in the incidence of complications between the groups receiving oseltamivir phosphate for treatment and the placebo group, in this category bolnyh.Net available information on treatment influenza in patients with severe health or conditions requiring hospitalization.
Profile of unwanted side effects in patients at risk was, in general, the same as in adult patients with younger age, without concomitant diseases.
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